When Dr. Nicholas Shaw joins a humanitarian medical outfit in Honduras, he hopes to recover from a recent traumatic event and help those in need. However, something sinister has followed Dr. Shaw...something evil that wishes to push his medical skills through a ghastly gauntlet. With bodies piling up, the doctor must battle with his family's past, medical abominations, and a serial killer on the loose. Can anyone make it out alive? A Legacy of Violence collects the entire twelve-issue maxi-series by the masters of horror, Cullen Bunn and Andrea Mutti.